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Items: 8

1.

Reduced diploidization and survival improvement of semi-cloned mice produced from androgenetic haploid embryonic stem cells

(Submitter supplied) We found that the overall DNA methylation and hydroxymethylation in AG-haESCs are extremely low, and the downregulation of both de novo methyltransferase Dnmt3b and methylation maintenance enzyme Dnmt1was discovered responsible for this DNA hypomethylation. Further, our study discovered that the correction of DNA methylation can greatly reduce the incidence of diploidization and further improve the survival of semi-cloned mice produced from AG-haESCs.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
6 Samples
Download data: TXT
Series
Accession:
GSE99588
ID:
200099588

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11109 Series
299307 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

2i ES XX rep2

Organism:
Mus musculus
Source name:
2i cultured embryonic stem cells (XX)
Platform:
GPL17021
Series:
GSE99588
Download data: TXT
Sample
Accession:
GSM2857266
ID:
302857266

SRA Run Selector

4.

2i ES XX rep1

Organism:
Mus musculus
Source name:
2i cultured embryonic stem cells (XX)
Platform:
GPL17021
Series:
GSE99588
Download data: TXT
Sample
Accession:
GSM2857265
ID:
302857265

SRA Run Selector

5.

Round_sperm RNA-Seq

Organism:
Mus musculus
Source name:
Round sperm
Platform:
GPL17021
Series:
GSE99588
Download data
Sample
Accession:
GSM2648136
ID:
302648136

SRA Run Selector

6.

AOS-16 RNA-Seq

Organism:
Mus musculus
Source name:
Androgenetic haploid embryonic stem cells (AG-haESCs)
Platform:
GPL17021
Series:
GSE99588
Download data
Sample
Accession:
GSM2648135
ID:
302648135

SRA Run Selector

7.

AOS-14 RNA-Seq

Organism:
Mus musculus
Source name:
Androgenetic haploid embryonic stem cells (AG-haESCs)
Platform:
GPL17021
Series:
GSE99588
Download data
Sample
Accession:
GSM2648134
ID:
302648134

SRA Run Selector

8.

A129-2 RNA-Seq

Organism:
Mus musculus
Source name:
Androgenetic haploid embryonic stem cells (AG-haESCs)
Platform:
GPL17021
Series:
GSE99588
Download data
Sample
Accession:
GSM2648133
ID:
302648133

SRA Run Selector

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db=gds|term=GSE99588[Accession]|query=1|qty=2|blobid=MCID_67349f9305a7200ef87954bb|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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