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Items: 12

1.

Intragenic DNA methylation prevents cryptic transcription initiations on gene bodies [DECAP-seq]

(Submitter supplied) In mammals, DNA methylation occurs mainly at 5mC of CpG dinucleotides. The methylation on the promoter leads to the suppression of gene expression, while the functional role of gene body DNA methylation in highly expressed genes has yet to be clarified. Here, we show that the Dnmt3b-dependent intragenic DNA methylation protects the gene body from RNA Polymerase II (RNA Pol II) spurious entry and cryptic transcription initiation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
10 Samples
Download data: BEDGRAPH
Series
Accession:
GSE72854
ID:
200072854
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

DECAPseq_ESC_KO_cytosol

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422541
ID:
302422541
4.

DECAPseq_ESC_KO_polyA

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422540
ID:
302422540
5.

DECAPseq_ESC_WT_shSetd2

Organism:
Mus musculus
Source name:
E14 mESC wt, Setd2 shRNA transfection
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422539
ID:
302422539
6.

DECAPseq_ESC_WT_shCTR

Organism:
Mus musculus
Source name:
E14 mESC wt, CTR shRNA transfection
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422538
ID:
302422538
7.

DECAPseq_ESC_KO_shDis3_Rrp6

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko, Dis3/Rrp6 shRNA transfection
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422537
ID:
302422537
8.

DECAPseq_ESC_KO_shCTR

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko, CTR shRNA transfection
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422536
ID:
302422536
9.

DECAPseq_ESC_KO_rep2

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422535
ID:
302422535
10.

DECAPseq_ESC_KO_rep1

Organism:
Mus musculus
Source name:
E14 mESC Dnmt3b ko
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422534
ID:
302422534
11.

DECAPseq_ESC_WT_rep2

Organism:
Mus musculus
Source name:
E14 mESC wt
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422533
ID:
302422533
12.

DECAPseq_ESC_WT_rep1

Organism:
Mus musculus
Source name:
E14 mESC wt
Platform:
GPL19057
Series:
GSE72854 GSE72856
Download data: BEDGRAPH
Sample
Accession:
GSM2422532
ID:
302422532
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Supplemental Content

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