GSE68631[Accession] - GEO DataSets - NCBI

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Items: 13

Select item 2000686311.

Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects.

(Submitter supplied) RNA interference (RNAi) is an evolutionarily conserved phenomenon of post-transcriptional gene silencing mediated by small interfering RNAs (siRNAs) generated from short hairpin RNAs (shRNAs) by Dicer cleavage. Here, we report that siRNA precursors can be divided into two categories with different processing mechanisms and silencing activities that are dependent on stem loop length. We designed an alternative siRNA precursor for triggering RNAi named single-stranded Argonaute2 (Ago2)-processed interfering RNA (saiRNA). more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL11154
11 Samples

Download data: TXT

Series

Accession:: GSE68631

ID:: 200068631

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10529 Series
183402 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3016778563.

saiLC-RZ small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677856

ID:: 301677856

SRA Run Selector

Select item 3016778554.

shLC-LC small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677855

ID:: 301677855

SRA Run Selector

Select item 3016778545.

shLC small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677854

ID:: 301677854

SRA Run Selector

Select item 3016778536.

saiGP-RZ small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677853

ID:: 301677853

SRA Run Selector

Select item 3016778527.

shGP-LC small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677852

ID:: 301677852

SRA Run Selector

Select item 3016778518.

shGP small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677851

ID:: 301677851

SRA Run Selector

Select item 3016778509.

con small RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677850

ID:: 301677850

SRA Run Selector

Select item 30167784910.

saiGP-RZ RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677849

ID:: 301677849

SRA Run Selector

Select item 30167784811.

shGP-LC RNA-seq

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677848

ID:: 301677848

SRA Run Selector

Select item 30167784712.

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677847

ID:: 301677847

SRA Run Selector

Select item 30167784613.

Organism:: Homo sapiens

Source name:: HEK293 cells total RNA

Platform:: GPL11154
Series:: GSE68631

Download data: TXT

Sample

Accession:: GSM1677846

ID:: 301677846

SRA Run Selector

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