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Items: 10

1.

Cyclin D1 determines estrogen dependent signaling in human breast cancer cell line MCF7

(Submitter supplied) The CCND1 gene, which is frequently overexpressed in cancers, encodes the regulatory subunit of a holoenzyme that phosphorylates the retinoblastoma protein (pRb). It is known that cyclin D1 regulates ERα transactivation using heterologous reporter systems, the significance of this observation to E2 dependent gene activation is unknow. E2 stimulated MCF7 cells treated with cyclin D1 siRNA in order to analyze the genes regulated by estradiol in a cyclin D1 dependent manner. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
8 Samples
Download data: CEL
Series
Accession:
GSE48989
ID:
200048989

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Homo sapiens
136 DataSets
1879 Series
27 Related Platforms
38399 Samples
Download data
Platform
Accession:
GPL6244
ID:
100006244

3.

MCF7 cyclin D1 siRNA Estradiol Rep2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191293
ID:
301191293

4.

MCF7 cyclin D1 siRNA Estradiol Rep1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191292
ID:
301191292

5.

MCF7 cyclin D1 siRNA Vehicle Rep2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191291
ID:
301191291

6.

MCF7 cyclin D1 siRNA Vehicle Rep1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191290
ID:
301191290

7.

MCF7 control siRNA Estradiol Rep2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191289
ID:
301191289

8.

MCF7 control siRNA Estradiol Rep1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191288
ID:
301191288

9.

MCF7 control siRNA Vehicle Rep2

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191287
ID:
301191287

10.

MCF7 control siRNA Vehicle Rep1

Organism:
Homo sapiens
Source name:
MCF7
Platform:
GPL6244
Series:
GSE48989
Download data: CEL
Sample
Accession:
GSM1191286
ID:
301191286

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