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Items: 1 to 20 of 30

1.

Single-cell multi-omics in human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

(Submitter supplied) Clonal hematopoiesis (CH) reflects clonal expansion of blood stem and progenitor cells with somatic mutations. We leveraged multi-modality single-cell sequencing to capture mutation status together with the transcriptome and methylome of CD34+ hematopoietic progenitor cells from five individuals with DNMT3A R882-mutated CH.
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL24247 GPL11154 GPL24676
26 Samples
Download data: CSV, MTX, TSV, TXT, XLSX
Series
Accession:
GSE158067
ID:
200158067

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
17049 Series
931958 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
14271 Series
696187 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10550 Series
183623 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

5.

CH04 Amplicon

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL11154
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM4790035
ID:
304790035

6.

CH04 10X

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL11154
Series:
GSE158067
Download data: MTX, TSV
Sample
Accession:
GSM4790031
ID:
304790031

7.

CH05 Amplicon [genotype]

Organism:
Homo sapiens
Source name:
Bone marrow aspirate from patient
Platform:
GPL24676
Series:
GSE158067
Download data: CSV
Sample
Accession:
GSM6251267
ID:
306251267

8.

CH05 ATAC

Organism:
Homo sapiens
Source name:
Bone marrow aspirate from patient
Platform:
GPL24676
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251266
ID:
306251266

9.

CH05 Amplicon

Organism:
Homo sapiens
Source name:
Bone marrow aspirate from patient
Platform:
GPL24676
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM5811753
ID:
305811753

10.

CH05 10X

Organism:
Homo sapiens
Source name:
Bone marrow aspirate from patient
Platform:
GPL24676
Series:
GSE158067
Download data: MTX, TSV
Sample
Accession:
GSM5811752
ID:
305811752

11.

Mouse WT3

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251265
ID:
306251265

SRA Run Selector

12.

Mouse WT2

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251264
ID:
306251264

SRA Run Selector

13.

Mouse WT1

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251263
ID:
306251263

SRA Run Selector

14.

Mouse MUT3

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251262
ID:
306251262

SRA Run Selector

15.

CH04_2 scRRBSseq

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL24676
Series:
GSE158067
Download data
Sample
Accession:
GSM4852371
ID:
304852371

16.

Mouse MUT2

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251261
ID:
306251261

SRA Run Selector

17.

CH02_2 scRRBSseq

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL24676
Series:
GSE158067
Download data
Sample
Accession:
GSM4852370
ID:
304852370

18.

Mouse MUT1

Organism:
Mus musculus
Source name:
Bone marrow from mouse
Platform:
GPL24247
Series:
GSE158067
Download data: TSV
Sample
Accession:
GSM6251260
ID:
306251260

SRA Run Selector

19.

CH04_1 scRREMseq

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL24676
Series:
GSE158067
Download data
Sample
Accession:
GSM4852369
ID:
304852369

20.

CH02_1 scRREMseq

Organism:
Homo sapiens
Source name:
GCSF mobilized stem cells from patient
Platform:
GPL24676
Series:
GSE158067
Download data
Sample
Accession:
GSM4852368
ID:
304852368

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