GSE149634[Accession] - GEO DataSets - NCBI

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Items: 9

Select item 2001496341.

Single cell mapping of breast tumor stroma reveals dynamically evolving compositions of cancer-associated fibroblasts along tumor progression (bulk RNA-seq dataset)

(Submitter supplied) Tumors are complex ecosystems, in which malignant and non-malignant cells engage in continuous interactions. Cancer associated fibroblasts (CAFs) are the most abundant non-malignant cells in the majority of carcinomas. The wide range of activities that CAFs perform suggests a dynamic and heterogeneous composition, yet tumor infiltrating CAF subpopulations remain poorly characterized. Here we used single cell RNA sequencing and index sorting to map CAFs at various stages of tumor progression and metastasis.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
7 Samples

Download data: XLSX

Series

Accession:: GSE149634

ID:: 200149634

SRA Run Selector

Select item 1000190572.

Illumina NextSeq 500 (Mus musculus)

Organism:: Mus musculus

10275 Series
295680 Samples

Platform

Accession:: GPL19057

ID:: 100019057

Select item 3045062443.

sample.21_GFPposEpCAMpos

Organism:: Mus musculus

Source name:: GFP+ EpCAM+ tumor derived cells (from 4T1-GFP tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506244

ID:: 304506244

SRA Run Selector

Select item 3045062434.

sample.20_GFPposEpCAMneg

Organism:: Mus musculus

Source name:: GFP+ EpCAM- tumor derived cells (from 4T1-GFP tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506243

ID:: 304506243

SRA Run Selector

Select item 3045062425.

sample.19_GFPnegEpCAMpos

Organism:: Mus musculus

Source name:: GFP- EpCAM+ tumor derived cells (from 4T1-GFP tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506242

ID:: 304506242

SRA Run Selector

Select item 3045062416.

sample.18_GFPnegEpCAMneg

Organism:: Mus musculus

Source name:: GFP- EpCAM- tumor derived cells (from 4T1-GFP tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506241

ID:: 304506241

SRA Run Selector

Select item 3045062407.

Organism:: Mus musculus

Source name:: PDPN- CAFs (from 4T1-luc tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506240

ID:: 304506240

SRA Run Selector

Select item 3045062398.

Organism:: Mus musculus

Source name:: PDPN+ CAFs (from 4T1-luc tumors)

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506239

ID:: 304506239

SRA Run Selector

Select item 3045062389.

Organism:: Mus musculus

Source name:: Normal mammary fat pad

Platform:: GPL19057
Series:: GSE149634 GSE149636

Sample

Accession:: GSM4506238

ID:: 304506238

SRA Run Selector

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