GSE146592[Accession] - GEO DataSets - NCBI

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Items: 17

Select item 2001465921.

Acute myeloid leukemia cells resist chemotherapy through a transient senescence-like state [PDX]

(Submitter supplied) In acute myeloid leukemias (AML), chemotherapy is frequently followed by disease relapse, yet the mechanism by which AML reemerges is not fully understood. We hypothesized that chemotherapy induces senescence-like dormancy that facilitates survival to genotoxic exposure, allowing AML cells to endure treatment in a transiently dormant state while retaining potential for leukemic repopulation. Here, we show that primary AML cells exhibit hallmark senescence features following treatment with cytarabine (AraC), including growth arrest, increased cellular granularity, senescence-associated-β-galactosidase (SA-β-gal) activity, and senescence-associated transcriptomic alterations. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
15 Samples

Download data: TXT

Series

Accession:: GSE146592

ID:: 200146592

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000167912.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12172 Series
349192 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3043963423.

AML1956_at_day_29_sample_2

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396342

ID:: 304396342

SRA Run Selector

Select item 3043963414.

AML1956_at_day_29_sample_1

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396341

ID:: 304396341

SRA Run Selector

Select item 3043963405.

AML1956_at_day_8_sample_1

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396340

ID:: 304396340

SRA Run Selector

Select item 3043963396.

AML1956_at_day_0_sample_3

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396339

ID:: 304396339

SRA Run Selector

Select item 3043963387.

AML1956_at_day_0_sample_2

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396338

ID:: 304396338

SRA Run Selector

Select item 3043963378.

AML1956_at_day_0_sample_1

Organism:: Homo sapiens

Source name:: primary AML1956

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396337

ID:: 304396337

SRA Run Selector

Select item 3043963369.

AML2837_at_day_29_sample_3

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396336

ID:: 304396336

SRA Run Selector

Select item 30439633510.

AML2837_at_day_29_sample_2

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396335

ID:: 304396335

SRA Run Selector

Select item 30439633411.

AML2837_at_day_29_sample_1

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396334

ID:: 304396334

SRA Run Selector

Select item 30439633312.

AML2837_at_day_8_sample_3

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396333

ID:: 304396333

SRA Run Selector

Select item 30439633213.

AML2837_at_day_8_sample_2

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396332

ID:: 304396332

SRA Run Selector

Select item 30439633114.

AML2837_at_day_8_sample_1

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396331

ID:: 304396331

SRA Run Selector

Select item 30439633015.

AML2837_at_day_0_sample_3

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396330

ID:: 304396330

SRA Run Selector

Select item 30439632916.

AML2837_at_day_0_sample_2

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396329

ID:: 304396329

SRA Run Selector

Select item 30439632817.

AML2837_at_day_0_sample_1

Organism:: Homo sapiens

Source name:: primary AML2837

Platform:: GPL16791
Series:: GSE146544 GSE146592

Download data: TXT

Sample

Accession:: GSM4396328

ID:: 304396328

SRA Run Selector

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GSE146592[Accession] (17)
GEO DataSets
serine/threonine-protein kinase 38 isoform X3 [Canis lupus familiaris]
serine/threonine-protein kinase 38 isoform X3 [Canis lupus familiaris]
gi|1952679539|ref|XP_038537673.1|

Protein
flagellar biosynthesis regulator FlhF [Xanthomonas oryzae pv. oryzae]
flagellar biosynthesis regulator FlhF [Xanthomonas oryzae pv. oryzae]
gi|1127104178|gb|OLI69838.1||gnl|WG Y|IXO151_13920

Protein
Uncultured Obesumbacterium sp. clone abc847 16S ribosomal RNA gene, partial sequ...
Uncultured Obesumbacterium sp. clone abc847 16S ribosomal RNA gene, partial sequence
gi|1774711180|gb|MN663616.1|

Nucleotide
BACKGROUND - Screening for Hepatocellular Cancer in Chronic Liver Disease: A Sys...
BACKGROUND - Screening for Hepatocellular Cancer in Chronic Liver Disease: A Systematic Review

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