GSE144841[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2001448411.

4EHP and GIGYF1/2 induce translation-coupled messenger RNA decay

(Submitter supplied) Although canonical mRNA degradation is generally recognized to be translation dependent, our understanding of the molecular events that coordinate ribosome movement with the decay machinery is still limited. Here, we show that the 4EHP–GIGYF1/2 complex triggers co-translational mRNA decay as a result of altered ribosome activity during elongation. Human cells lacking 4EHP and GIGYF1 and 2 proteins accumulate transcripts known to be degraded in a translation dependent manner or with prominent ribosome pausing. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other

Platform:: GPL21290
12 Samples

Download data: TXT

Series

Accession:: GSE144841

ID:: 200144841

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000212902.

Illumina HiSeq 3000 (Homo sapiens)

Organism:: Homo sapiens

1138 Series
28241 Samples

Platform

Accession:: GPL21290

ID:: 100021290

Select item 3042991363.

GIGYF1/2-null replicate 2 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299136

ID:: 304299136

SRA Run Selector

Select item 3042991354.

GIGYF1/2-null replicate 1 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299135

ID:: 304299135

SRA Run Selector

Select item 3042991345.

4EHP-null replicate 2 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299134

ID:: 304299134

SRA Run Selector

Select item 3042991336.

4EHP-null replicate 1 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299133

ID:: 304299133

SRA Run Selector

Select item 3042991327.

Wild-type replicate 2 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299132

ID:: 304299132

SRA Run Selector

Select item 3042991318.

Wild-type replicate 1 for Ribo-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299131

ID:: 304299131

SRA Run Selector

Select item 3042991309.

GIGYF1/2-null replicate 2 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299130

ID:: 304299130

SRA Run Selector

Select item 30429912910.

GIGYF1/2-null replicate 1 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299129

ID:: 304299129

SRA Run Selector

Select item 30429912811.

4EHP-null replicate 2 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299128

ID:: 304299128

SRA Run Selector

Select item 30429912712.

4EHP-null replicate 1 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299127

ID:: 304299127

SRA Run Selector

Select item 30429912613.

Wild-type replicate 2 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299126

ID:: 304299126

SRA Run Selector

Select item 30429912514.

Wild-type replicate 1 for RNA-seq

Organism:: Homo sapiens

Source name:: HEK293T

Platform:: GPL21290
Series:: GSE144841

Sample

Accession:: GSM4299125

ID:: 304299125

SRA Run Selector

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GSE144841[Accession] (14)
GEO DataSets
GALNT4 [Tympanuchus pallidicinctus]
GALNT4 [Tympanuchus pallidicinctus]
Gene ID:128073507

Gene

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