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Items: 10

1.

Functional dissection of MIEN1 trans-regulation provides new evidence for colorectal cancer genome editing-based therapeutics

(Submitter supplied) MIEN1 has been described as a key actor in colorectal cancer (CRC) biogenesis. We have used CRISPR/Cas9 technique to delete the promoter region of MIEN1 in HT-29 CRC cells. RNA-seq experiments revealed that several biological processes related to migration/metastasis were enriched by differentially expressed genes. Genetically modified cells shown decreased migration capacity.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
8 Samples
Download data: TXT
Series
Accession:
GSE123734
ID:
200123734
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

HT-29_KO_MIEN1_4

Organism:
Homo sapiens
Source name:
HT-29 cells KO MIEN1 replicate 4
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510406
ID:
303510406
4.

HT-29_KO_MIEN1_3

Organism:
Homo sapiens
Source name:
HT-29 cells KO MIEN1 replicate 3
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510405
ID:
303510405
5.

HT-29_KO_MIEN1_2

Organism:
Homo sapiens
Source name:
HT-29 cells KO MIEN1 replicate 2
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510404
ID:
303510404
6.

HT-29_KO_MIEN1_1

Organism:
Homo sapiens
Source name:
HT-29 cells KO MIEN1 replicate 1
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510403
ID:
303510403
7.

HT-29_WT_4

Organism:
Homo sapiens
Source name:
HT-29 cells wild-type replicate 4
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510402
ID:
303510402
8.

HT-29_WT_3

Organism:
Homo sapiens
Source name:
HT-29 cells wild-type replicate 3
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510401
ID:
303510401
9.

HT-29_WT_2

Organism:
Homo sapiens
Source name:
HT-29 cells wild-type replicate 2
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510400
ID:
303510400
10.

HT-29_WT_1

Organism:
Homo sapiens
Source name:
HT-29 cells wild-type replicate 1
Platform:
GPL24676
Series:
GSE123734
Download data: TXT
Sample
Accession:
GSM3510399
ID:
303510399
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Supplemental Content

db=gds|term=GSE123734[Accession]|query=26|qty=2|blobid=MCID_6737119a5ff35f4f672b73b0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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