GPL6603[Accession] - GEO DataSets

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Select item 2000205981.

5-azacytidine treatment reorganizes genomic histone modification patterns

(Submitter supplied) Methylation of DNA in combination with histone modifications establishes an epigenetic code that ensures the proper control of gene expression. Although DNA methyltransferases have been shown to interact with histone methyltransferases such as EZH2 (which methylates histone H3 on lysine 27) and G9a (which methylates histone H3 on lysine 9), the relationship between DNA methylation and repressive histone marks has not been fully studied. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array; Methylation profiling by genome tiling array; Expression profiling by array

Platforms:: GPL6603 GPL6883
11 Samples

Download data: PAIR, TXT

Series

Accession:: GSE20598

ID:: 200020598

Select item 2000195622.

Comparative ChIP-chip analysis of general transcription factor TFIIB and negative cofactor NC2 in human B cells

(Submitter supplied) A comparative ChIP-chip analysis of TFIIB and NC2 in human B cells reveals that basal core promoter architectures control the equilibrium between NC2 and preinitiation complexes. We conducted a comparative ChIP-chip and gene expression analysis of TFIIB in human B cells and analyze associated core promoter architectures. TFIIB occupancy relates well to gene expression, with the vast majority of promoters being GC-rich and lacking defined core promoter elements. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6603
3 Samples

Download data: TXT

Series

Accession:: GSE19562

ID:: 200019562

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000122243.

p53 and p73 ChIP-chip experiments in HCT116-3(6) cells

(Submitter supplied) The p53-family of transcription factors share a highly homologous DNA binding domain and have overlapping and distinct biological functions. Using chromatin immunoprecipitation in combination with NimbleGen promoter arrays and a Model-based Algorithm for Promoter arrays (MAP), we performed a direct comparison of the promoter occupancy profiles of p53 and p73 before and after treatment with hydroxyurea (HU). more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6603
4 Samples

Download data: TXT

Series

Accession:: GSE12224

ID:: 200012224

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000108874.

H3K9acetyl ChIP on chip for integrative epigenomic study in leukemia samples

(Submitter supplied) The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation is a hallmark of cancer and plays a central role in determining tumor phenotype. We predicted that integration of different genome-wide epigenetic regulatory marks along with gene expression levels would provide greater power in capturing biological differences between leukemia subtypes. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL6603
8 Samples

Download data: PAIR

Series

Accession:: GSE10887

ID:: 200010887

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000066035.

HGS17_min_promoter_set

(Submitter supplied) ChIP-chip promoter microarray based on the HG17 genome build (May 2004) covering approximately 1.5 kb around the transcription start site Protocol: See Roche NimbleGen website

Organism:: Homo sapiens

4 Series
20 Samples

Download data: NDF, NGD, POS

Platform

Accession:: GPL6603

ID:: 100006603

Select item 3005173326.

HEK293 5-azaC H3K9me3 [ChIP-chip]

Organism:: Homo sapiens

Source name:: H3K9me3 ChIP DNA from HEK293 cells treated with 5 uM 5-azacytidine for 8 days (channel 1) Total input DNA from HEK293 cells treated with 5uM 5-azacytidine for 8 days (channel 2)

Platform:: GPL6603
Series:: GSE20598

Download data: PAIR

Sample

Accession:: GSM517332

ID:: 300517332

Select item 3005173317.

HEK293 5-azaC H3K27me3 [ChIP-chip]

Organism:: Homo sapiens

Source name:: H3K27me3 ChIP DNA from HEK293 cells treated with 5 uM 5-azacytidine for 8 days (channel 1) Total input DNA from HEK293 cells treated with 5uM 5-azacytidine for 8 days (channel 2)

Platform:: GPL6603
Series:: GSE20598

Download data: PAIR

Sample

Accession:: GSM517331

ID:: 300517331

Select item 3005173308.

HEK293 aa 5-meC [ChIP-chip]

Organism:: Homo sapiens

Source name:: 5-meC MeDIP DNA from HEK293 cells treated with 50% acetic acid (control) (channel 1) Total input DNA from HEK293 cells treated with 50% acetic acid (channel 2)

Platform:: GPL6603
Series:: GSE20598

Download data: PAIR

Sample

Accession:: GSM517330

ID:: 300517330

Select item 3005173299.

HEK293 aa H3K9me3 [ChIP-chip]

Organism:: Homo sapiens

Source name:: H3K9me3 ChIP DNA from HEK293 cells treated with 50% acetic acid (control) (channel 1) Total input DNA from HEK293 cells treated with 50% acetic acid (channel 2)

Platform:: GPL6603
Series:: GSE20598

Download data: PAIR

Sample

Accession:: GSM517329

ID:: 300517329

Select item 30051732810.

HEK293 aa H3K27me3 [ChIP-chip]

Organism:: Homo sapiens

Source name:: H3K27me3 ChIP DNA from HEK293 cells treated with 50% acetic acid (control) (channel 1) Total input DNA from HEK293 cells treated with 50% acetic acid (channel 2)