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Items: 1 to 20 of 109

1.

Ares Swanson MBNL mutant study

(Submitter supplied) MBNL1 is a known splicing factor and is related to Myotonic Dystrophy (DM). This study examines the tissue specific splicing patterns of MBNL1 using a mutant and wild type mouse across three tissues (heart,brain,quadricep) related publications: Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy. Du H, etal Nat Struct Mol Biol. 2010 Feb;17(2):187-93. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2720
18 Samples
Download data: CEL
Series
Accession:
GSE28640
ID:
200028640

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Alternative splicing and gene expression in a mouse model of myotonic dystrophy

(Submitter supplied) Distinct RNA-mediated impacts on alternative splicing and extracellular matrix gene expression in a mouse model of myotonic dystrophy. Myotonic dystrophy (DM1) is associated with expression of expanded CTG DNA repeats as RNA (CUGexp RNA). To test whether CUGexp RNA creates a global splicing defect, we compared skeletal muscle of two mouse DM1 models, one expressing a CTGexp transgene, and another homozygous for a defective Mbnl1 gene. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2720
12 Samples
Download data: CEL
Series
Accession:
GSE17986
ID:
200017986

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Ultraconserved elements are associated with control of splicing regulators by alt splicing and nonsense mediated decay

(Submitter supplied) We blocked nonsense-mediated mRNA decay (NMD) pathway and used a custom alternative transcript sensitive Affymetrix microarray to seek alternatively spliced RNAs whose levels increased compared to controls. Keywords: Nonsense Mediated Decay (NMD)
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2720
10 Samples
Download data: CEL
Series
Accession:
GSE6611
ID:
200006611

PubMed Full text in PMC Similar studies Analyze with GEO2R

4.

Mouse Alt-Splice Tissue Panel (Brain vs Non-Brain)

(Submitter supplied) 22 Normal adult mouse tissues on custom alternative transcript sensitive Affymetrix microarray used to address differeneces in tissue specific alternative splicing. Abstract: Alternative splicing contributes to both gene regulation and protein diversity. To discover broad relationships between regulation of alternative splicing and sequence conservation, we applied a systems approach, using oligonucleotide microarrays designed to capture splicing information across the mouse genome. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL2720
64 Samples
Download data
Series
Accession:
GSE3063
ID:
200003063

PubMed Full text in PMC Similar studies Analyze with GEO2R

5.

ares_ucsc_mouse_59198_affyMouseA

(Submitter supplied) Affymetrix Standard Protocol
Organism:
Mus musculus
4 Series
104 Samples
Download data
Platform
Accession:
GPL2720
ID:
100002720

6.

brain_mut3

Organism:
Mus musculus
Source name:
mouse brain mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709669
ID:
300709669

7.

brain_mut2

Organism:
Mus musculus
Source name:
mouse brain mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709668
ID:
300709668

8.

brain_mut1

Organism:
Mus musculus
Source name:
mouse brain mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709667
ID:
300709667

9.

brain_wt3

Organism:
Mus musculus
Source name:
mouse brain wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709666
ID:
300709666

10.

brain wt2

Organism:
Mus musculus
Source name:
mouse brain wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709665
ID:
300709665

11.

brain_wt1

Organism:
Mus musculus
Source name:
mouse brain wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709664
ID:
300709664

12.

quad_mut3

Organism:
Mus musculus
Source name:
mouse quad mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709663
ID:
300709663

13.

quad_mut2

Organism:
Mus musculus
Source name:
mouse quad mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709662
ID:
300709662

14.

quad_mut1

Organism:
Mus musculus
Source name:
mouse quad mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709661
ID:
300709661

15.

quad_wt3

Organism:
Mus musculus
Source name:
mouse quad wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709660
ID:
300709660

16.

quad_wt2

Organism:
Mus musculus
Source name:
mouse quad wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709659
ID:
300709659

17.

quad_wt1

Organism:
Mus musculus
Source name:
mouse quad wt
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709658
ID:
300709658

18.

heart_mut3

Organism:
Mus musculus
Source name:
mouse heart mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709657
ID:
300709657

19.

heart_mut2

Organism:
Mus musculus
Source name:
mouse heart mut
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709656
ID:
300709656

20.

heart_mut1

Organism:
Mus musculus
Source name:
mouse heart mutant
Platform:
GPL2720
Series:
GSE28640
Download data: CEL
Sample
Accession:
GSM709655
ID:
300709655

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