GEO DataSets

(Submitter supplied) Background: Penicillins inhibit cell wall synthesis; therefore, H. pylori must be dividing for these antibiotics to be effective. Identifying growth responses to varying medium pH may allow design of more effective treatment regimens. Aim: To determine the effect of acidity on bacterial growth and the bactericidal efficacy of ampicillin. Methods: H. pylori were incubated in dialysis chambers suspended in 1.5L of media at various pHs with 5mM urea, with or without ampicillin, for 4, 8 or 16 hours, thus mimicking unbuffered gastric juice. more...

Organism:

Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093

Type:

Expression profiling by array

Platform:

GPL15831

22 Samples

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