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Items: 1 to 20 of 37

1.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Quercus alba; Trypanosoma cruzi; Bothrops moojeni; Pachymenia carnosa; Rhodotorula; Bos taurus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Gallus gallus; Oryctolagus cuniculus; Mus musculus; Human immunodeficiency virus 1; unidentified; Megathura crenulata; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus
Type:
Protein profiling by protein array
Platforms:
GPL23565 GPL23566
55 Samples
Download data: GPR
Series
Accession:
GSE100438
ID:
200100438

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VII

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Trypanosoma cruzi; Gallus gallus; Pachymenia carnosa; Quercus alba; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Dermestes lardarius; Ovis aries; Oryctolagus cuniculus; Megathura crenulata; Frangula alnus
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100310
ID:
200100310

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies VI

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Quercus alba; Oryctolagus cuniculus; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100309
ID:
200100309

PubMed Full text in PMC Similar studies Analyze with GEO2R

4.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies V

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Homo sapiens; Bos taurus; Rhodotorula; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Gossypium hirsutum; Oryctolagus cuniculus; Megathura crenulata
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100308
ID:
200100308

PubMed Full text in PMC Similar studies Analyze with GEO2R

5.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies IV

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Trypanosoma cruzi; Bos taurus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Rhodotorula; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE100307
ID:
200100307

PubMed Full text in PMC Similar studies Analyze with GEO2R

6.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies III

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Trypanosoma cruzi; Gallus gallus; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Oncorhynchus nerka; Sus scrofa domesticus; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Quercus alba; Oryctolagus cuniculus; Megathura crenulata
Type:
Protein profiling by protein array
Platform:
GPL23566
7 Samples
Download data: GPR, TXT
Series
Accession:
GSE99874
ID:
200099874

PubMed Full text in PMC Similar studies Analyze with GEO2R

7.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies II

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Homo sapiens; Bos taurus; Quercus alba; Gossypium hirsutum; Oncorhynchus nerka; Pandalus borealis; Gallus gallus; Sus scrofa domesticus; Ovis aries; Oryctolagus cuniculus; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Dermestes lardarius; Rhodotorula; Trypanosoma cruzi; Mus musculus; Human immunodeficiency virus 1; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL23566
14 Samples
Download data: GPR, TXT
Series
Accession:
GSE99873
ID:
200099873

PubMed Full text in PMC Similar studies Analyze with GEO2R

8.

Therapeutic antibodies to ganglioside GD2 evolved from highly selective germline antibodies I

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to evaluate the immunological evolution of antibodies to the glyco-antigen GD2. The goal is to determine germline and affinity mature antibody specificity and affinities/ Results: Affinity mature anti-GD2 antibodies 3F8 and ch14.18 had high affinity and were highly specific for the target GD2. Germline antibodies were also hihgly specific and had surprisingly high affinity. more...
Organism:
Trypanosoma cruzi; Rhodotorula; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Ceratonia siliqua; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Gallus gallus; Ovis aries; Oryctolagus cuniculus; unidentified; Megathura crenulata; Frangula alnus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Sus scrofa domesticus
Type:
Protein profiling by protein array
Platform:
GPL23565
6 Samples
Download data: GPR, TXT
Series
Accession:
GSE99872
ID:
200099872

PubMed Full text in PMC Similar studies Analyze with GEO2R

9.

Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to profile anti-glycan immune responses to whole-cell vaccines: GVAX Pancreas, K562-GM and H1299. The aim was to indentify anti-glycan antibody responses relevent to patient clinical outcomes Results: Immune responses to non-human antigens bovine fetuin and alpha-Gal antigens were identified induced by GVAX Pancreas. The magnitude of these responses inversely correlate with patient survival. more...
Organism:
Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Homo sapiens; Bos taurus; Mus musculus; Human immunodeficiency virus 1; Quercus alba; Oryctolagus cuniculus; Megathura crenulata
Type:
Other
Platform:
GPL21991
168 Samples
Download data: GPR, TXT
Series
Accession:
GSE83087
ID:
200083087

PubMed Full text in PMC Similar studies Analyze with GEO2R

10.

A Simple, Inexpensive Strategy for Predicting Potential Beneficial Clinical Responses on Prostate Cancer Vaccine Therapy

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Quercus alba; Megathura crenulata; Pandalus borealis; Oncorhynchus nerka; Ovis aries; Ceratonia siliqua; Frangula alnus; Senegalia senegal; Dermestes lardarius; Trypanosoma cruzi; Gallus gallus; Bothrops moojeni; Pachymenia carnosa
Type:
Other
Platforms:
GPL20117 GPL20116
331 Samples
Download data
Series
Accession:
GSE68405
ID:
200068405

PubMed Full text in PMC Similar studies

11.

Determination of ABO blood type for prostate cancer patients

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to assign ABO blood type to patients from a clinical trial on PROSTVAC. The goal is to determine if blood type correlates with survival for patients treated with PROSTVAC Results: Blood types were assigned and type B and O patients were found to have longer survival than type A and AB patients Conclusion: Blood type may serve as a convenient method to identify patients likely to respond favorably to PROSTVAC therapy
Organism:
Homo sapiens; Gallus gallus; Frangula alnus
Type:
Other
Platform:
GPL20117
111 Samples
Download data: TXT
Series
Accession:
GSE68404
ID:
200068404

PubMed Full text in PMC Similar studies

12.

Development of a glycan microarray based method for ABO blood typing

(Submitter supplied) Purpose: This study uses a high-throughput glycan microarray to develop a novel method to assign ABO blood type. The method will then be applied to samples from patients treated with PROSTVAC to determine if blood type correlates with survival Results: Many blood group A and B antigens correlate with blood type. Blood typing is best achieved using a combination of 10 signals Conclusion: ABO blood type can be determined with greater than 97% accuracy using only 4 microliters of serum.
Organism:
Trypanosoma cruzi; Bos taurus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Oncorhynchus nerka; Homo sapiens; Gallus gallus; Ovis aries; Ceratonia siliqua; Megathura crenulata; Frangula alnus; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius
Type:
Other
Platform:
GPL20116
220 Samples
Download data: TXT
Series
Accession:
GSE68403
ID:
200068403

PubMed Full text in PMC Similar studies

13.

Anti-glycan humoral responses after vaccination with PROSTVAC-VF

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Medicago sativa; Gallus gallus; Megathura crenulata; Gossypium hirsutum; Pandalus borealis; Homo sapiens; Quercus alba; Bothrops moojeni; Pachymenia carnosa; Rhodotorula; Bos taurus; Ovis aries; Mus musculus; Frangula alnus; Senegalia senegal; Dermestes lardarius
Type:
Protein profiling by protein array
Platforms:
GPL16242 GPL16262
564 Samples
Download data: TXT
Series
Accession:
GSE50410
ID:
200050410

Analyze with GEO2R

14.

Post-vaccination serum anti-glycan total Ig antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:200)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Quercus alba; Ovis aries; Megathura crenulata; Pandalus borealis; Frangula alnus; Senegalia senegal; Dermestes lardarius; Medicago sativa; Gallus gallus; Bothrops moojeni; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL16242
113 Samples
Download data
Series
Accession:
GSE50239
ID:
200050239

Analyze with GEO2R

15.

Baseline serum anti-glycan IgM antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Homo sapiens; Bos taurus; Quercus alba; Gossypium hirsutum; Medicago sativa; Pandalus borealis; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Dermestes lardarius; Rhodotorula; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa
Type:
Protein profiling by protein array
Platform:
GPL16242
113 Samples
Download data
Series
Accession:
GSE50237
ID:
200050237

Analyze with GEO2R

16.

Baseline serum anti-glycan total Ig antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Rhodotorula; Bos taurus; Mus musculus; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Medicago sativa; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Quercus alba; Gossypium hirsutum; Pandalus borealis; Homo sapiens
Type:
Protein profiling by protein array
Platform:
GPL16242
113 Samples
Download data
Series
Accession:
GSE50236
ID:
200050236

Analyze with GEO2R

17.

Post-vaccination serum anti-glycan IgG antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Quercus alba; Bothrops moojeni; Pachymenia carnosa; Gossypium hirsutum; Pandalus borealis; Homo sapiens; Medicago sativa; Gallus gallus; Ovis aries; Megathura crenulata; Frangula alnus; Rhodotorula; Bos taurus; Mus musculus; Senegalia senegal; Dermestes lardarius
Type:
Protein profiling by protein array
Platform:
GPL16242
113 Samples
Download data
Series
Accession:
GSE50235
ID:
200050235

Analyze with GEO2R

18.

Post-vaccination serum anti-glycan total Ig antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:200)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Quercus alba; Bothrops moojeni; Pachymenia carnosa; Pandalus borealis; Gallus gallus; Homo sapiens; Gossypium hirsutum; Rhodotorula; Mus musculus; Bos taurus; Ovis aries; Megathura crenulata; Frangula alnus; Senegalia senegal; Dermestes lardarius
Type:
Protein profiling by protein array
Platform:
GPL16262
28 Samples
Download data
Series
Accession:
GSE50233
ID:
200050233

Analyze with GEO2R

19.

Post-vaccination serum anti-glycan total Ig antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Pachymenia carnosa; Dermestes lardarius; Ovis aries; Megathura crenulata; Frangula alnus; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Gallus gallus
Type:
Protein profiling by protein array
Platform:
GPL16262
28 Samples
Download data
Series
Accession:
GSE50232
ID:
200050232

Analyze with GEO2R

20.

Post-vaccination serum anti-glycan IgM antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine. (Dilution = 1:50)

(Submitter supplied) Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. This study uses a high-throughput glycan microarray to assess correlations between a subject's overall survival after receiving PROSTVAC-VF and his anti-glycan humoral responses occuring in the first months after treatment with PROSTVAC-VF. more...
Organism:
Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Dermestes lardarius; Gallus gallus; Pachymenia carnosa; Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Ovis aries; Megathura crenulata; Frangula alnus
Type:
Protein profiling by protein array
Platform:
GPL16262
28 Samples
Download data
Series
Accession:
GSE50231
ID:
200050231

Analyze with GEO2R

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