Table 1H. pylori type IV system

ProteinApparent mol wt (kDa)LocalizationBiochemical interaction and/or functionVir homologReferences
CagE101Inner membrane?Required for NF-κB activation and IL-8 induction; nucleoside triphosphate hydrolases (putative)VirB467, 93
CagT34Outer membrane?Lipoprotein (putative); chaperone (putative); required for the stability of other components (putative)VirB720, 58
HP52863Inner and outer membrane?Interacts with other components (putative)VirB920, 58
HP527207Inner membraneInteracts with other components (putative); thermostability (putative)VirB1020, 58
HP52538Inner membraneNucleoside triphosphate hydrolases; form hexameric assembliesVirB1153, 54
HP52490Inner membrane?Nucleoside triphosphate hydrolases (putative); required for CagA transportationVirD420, 58

From: Chapter 20, Alternative Mechanisms of Protein Release

Cover of Helicobacter pylori
Helicobacter pylori: Physiology and Genetics.
Mobley HLT, Mendz GL, Hazell SL, editors.
Washington (DC): ASM Press; 2001.
Copyright © 2001, ASM Press.

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