| LILR | Alias | Alleles | Expression | Action | Ligand |
|---|---|---|---|---|---|
| LILRA1 | LIR-6 | 3 | Monocytes, B cells | Activating | ? |
| LILRA2 | ILT1, LIR-7 | 7 | Myeloid lineage | Activating | FcE |
| LILRA3 | ILT6, LIR-4, HM31, HM43 | 12 | NK, T, Mono | ? Activating | ? |
| LILRA4 | ILT7 | 3 | Activating | ? | |
| LILRB1 | ILT2, CD85, LIR-1, MIR-7 | 8 | NK, T, B, Mono | Inhibiting | HLA Class I, cmv-UL18 |
| LILRB2 | ILT4, LIR-2, MIR-10 | 6 | Monocytes, dendritic cells | Inhibiting a | HLA A, B, G, (cmv-UL18) |
| LILRB3 | ILT5, LIR-3 | 21 | Monocytes, NK? | Inhibiting | not HLA |
| LILRB4 | ILT3, LIR-5, HM18 | 6 | Monocytes, Dendritic cells | Inhibitinga | ? |
| LILRB5 | LIR-8 | 2 | NK | Inhibiting | ? |
| ILT8 | 1 | Activating | ? | ||
| ILT9 | 1 | NA | n/a | ||
| ILT10 | 1 | ? | ? | ||
| ILT11 | 1 | ? | ? |
LILR: leukocyte immunoglobulin-like receptor; ILT: immunoglobulin-like transcript; LIR: leukocyte inhibitory receptor; MIR: macrophage inhibitory receptor; NA: not applicable.
aMay be involved in suppressing, rather than preventing an immune response (207).
From: The KIR Gene Cluster
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