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Select item 14152801.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 14589842.

GeneReviews® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2024.

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Select item 44036683.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2024 Jan-.

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Select item 34012944.

Endotext [Internet].

Feingold KR, Anawalt B, Blackman MR, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 18602425.

WormBook: The Online Review of C. elegans Biology [Internet].

Pasadena (CA): WormBook; 2005-2018.

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Select item 16686906.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

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Select item 53216727.

Essentials of Glycobiology [Internet]. 4th edition.

Varki A, Cummings RD, Esko JD, et al., editors.

Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.

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Select item 28215248.

PDQ Cancer Information Summaries [Internet].

Bethesda (MD): National Cancer Institute (US); 2002-.

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Select item 29807929.

Chromosomal Variation in Man: A Catalog of Chromosomal Variants and Anomalies: Online NLM Version [Internet].

Borgaonkar DS.

Bethesda (MD): National Center for Biotechnology Information (US); 1975-.

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Select item 265918210.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 548293011.

Glycoscience Protocols (GlycoPODv2) [Internet].

Nishihara S, Angata K, Aoki-Kinoshita KF, et al., editors.

Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021-.

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Select item 404875612.

The management of individuals with enduring moderate to severe mental health needs: a participatory evaluation of client journeys and the interface of mental health services with the criminal justice system in Cornwall.

Lea S, Callaghan L, Eick S, et al.

Southampton (UK): NIHR Journals Library; 2015 Apr. (Health Services and Delivery Research, No. 3.15.)

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Select item 477417813.

Births and their outcomes by time, day and year: a retrospective birth cohort data linkage study.

Macfarlane A, Dattani N, Gibson R, et al.

Southampton (UK): NIHR Journals Library; 2019 May. (Health Services and Delivery Research, No. 7.18.)

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Select item 310819414.

Registries for Evaluating Patient Outcomes: A User's Guide [Internet]. 3rd edition.

Gliklich RE, Dreyer NA, Leavy MB, editors.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 Apr.

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Select item 547163215.

Updated Recommendations on Treatment of Adolescents and Children with Chronic HCV Infection, and HCV Simplified Service Delivery and Diagnostics [Internet].

Geneva: World Health Organization; 2022.

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Select item 238715616.

Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition.

Noebels JL, Avoli M, Rogawski MA, et al., editors.

Bethesda (MD): National Center for Biotechnology Information (US); 2012.

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Select item 442776817.

WHO Guidelines on Hepatitis B and C Testing.

Geneva: World Health Organization; 2017 Feb.

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Select item 188138218.

Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition.

Siegel GJ, Agranoff BW, Albers RW, et al., editors.

Philadelphia: Lippincott-Raven; 1999.

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Select item 261902619.

Biosocial Surveys.

National Research Council (US) Committee on Advances in Collecting and Utilizing Biological Indicators and Genetic Information in Social Science Surveys; Weinstein M, Vaupel JW, Wachter KW, editors.

Washington (DC): National Academies Press (US); 2008.

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Select item 328969420.

Assessing Genetic Risks: Implications for Health and Social Policy.

Institute of Medicine (US) Committee on Assessing Genetic Risks; Andrews LB, Fullarton JE, Holtzman NA, et al., editors.

Washington (DC): National Academies Press (US); 1994.

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Supplemental Content

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Figure 1:

Overview of linkage analysis by Smith degradation. The sites that are cleaved by Smith degradation are indicated by red bars. A partially cleaved site is indicated by a dotted bar. CH₂OH-CHOH-CH₂-PA is also produced from 6-substituted hexoses because the CHO-CHOH bond in CHO-CHOH-CH₂-PA is rather stable against periodate oxidation compared with the CHOH-CHOH bond.

Smith degradation for glycan linkage analysis.

Nishihara S, Angata K, Aoki-Kinoshita KF, et al., editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021-.
Figure 38.6

Methylation analysis: A chemical approach to elucidating the glycosidic linkage positions in glycans.

Principles of Structural Analysis and Sequencing of Glycans.

Varki A, Cummings R, Esko J, et al., editors. Essentials of Glycobiology. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1999.
FIGURE 1-3

Linkage map of the rat, which is based on literature and recent unpublished information. Except where indicated, the linkages shown have not yet been assigned to chromosomes. An enlargement of RT1 is given below linkage group IX (''*"). Linkage data for Es-6, Ir-JHM, RT3, and Tbm-2 have been established by recombinant inbred strain analysis. Brackets indicate that the position of one of the two genes with respect to other genes within this linkage group has not been verified. The assignment of linkage groups I, VIII, and IX to chromosomes 1, 6, and 14, respectively, is based on Levan et al. (1986). Map compiled by H. J. Hedrich, Central Institute for Laboratory Animal Breeding, Hannover, Federal Republic of Germany (1988).

Introduction.

National Research Council (US) Committee on Immunologically Compromised Rodents. Immunodeficient Rodents: A Guide to Their Immunobiology, Husbandry, and Use. Washington (DC): National Academies Press (US); 1989.
Figure 7-16Genetic linkage analysis using an RFLP marker

In this procedure one studies the coinheritance of a specific human phenotype (here a genetic disease) with an RFLP marker. If individuals who inherit the disease nearly always inherit the RFLP marker, then the gene causing the disease and the RFLP marker are likely to be close together on the chromosome, as shown here. To prove that an observed linkage is statistically significant, hundreds of individuals may need to be examined. Note that the linkage will not be absolute unless the RFLP marker is located in the gene itself. Thus, occasionally the RFLP marker will be separated from the disease gene by meiotic crossing-over during the formation of the egg or sperm: this has happened in the case of the chromosome pair on the far right.

Nucleic Acid Hybridization .

Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell. 3rd edition. New York: Garland Science; 1994.