5FP3: Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases

PDB ID: 5FP3Download
MMDB ID: 136069
PDB Deposition Date: 2015/11/27
Updated in MMDB: 2019/10
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5FP3: monomeric; determined by author and by software (PISA)
Molecular Components in 5FP3
Label Count Molecule
Protein (1 molecule)
1
Human Lysine-specific Demethylase 6B, Jmjd3
(Gene symbol: KDM6B)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid
2
1
ZINC IONZINC ION
3
1
MAGNESIUM IONMAGNESIUM ION
4
2
BICINEBICINE
5
1
COBALT (II) IONCOBALT (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303