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4UW1:
X-ray crystal structure of human TNKS in complex with a small molecule inhibitor
PDB ID:
4UW1
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MMDB ID:
130690
PDB Deposition Date:
2014/8/8
Updated in MMDB:
2015/07
Experimental Method:
x-ray diffraction
Resolution:
3.37 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4UW1: monomeric; determined by author and by software (PISA)
Molecular Components in 4UW1
Label
Count
Molecule
Protein (1 molecule)
A
1
Tankyrase-1
(Gene symbol:
TNKS
)
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC ION
2
1
GLYCEROL
3
2
1,2-ETHANEDIOL
4
1
3-{4-[(dimethylamino)methyl]phenyl}-5-methoxyisoquinolin-1(2H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303