4TOS: Crystal structure of Tankyrase 1 with 355

PDB ID: 4TOSDownload
MMDB ID: 129457
PDB Deposition Date: 2014/6/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.802  Å
Source Organism:
Similar Structures:
Biological Unit for 4TOS: monomeric; determined by author and by software (PISA)
Molecular Components in 4TOS
Label Count Molecule
Protein (1 molecule)
1
Tankyrase-1
(Gene symbol: TNKS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamidetrans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303