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8B9Z: Drosophila melanogaster complex I in the Active state (Dm1)

PDB ID:	8B9Z Download
MMDB ID:	225522
PDB Deposition Date:	2022/10/10
Updated in MMDB:	2024/10
Experimental Method:	electron microscopy
Resolution:	3.28 Å
Source Organism:	Drosophila melanogaster
Similar Structures:

Biological Unit for 8B9Z: 43-meric; determined by author

Molecular Components in 8B9Z
Label	Count	Molecule
Proteins (43 molecules)
A	1	Nadh-ubiquinone Oxidoreductase Chain 3
B	1	Ld31474p
C	1	Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 3, Mitochondrial
D	1	Complex I-49kd
E	1	Nadh Dehydrogenase (Ubiquinone) 24 KDA Subunit, Isoform a
F	1	Nadh Dehydrogenase [ubiquinone] Flavoprotein 1, Mitochondrial
G	1	Nadh-ubiquinone Oxidoreductase 75 KDA Subunit, Mitochondrial
H	1	Nadh-ubiquinone Oxidoreductase Chain 1
I	1	Nadh Dehydrogenase (Ubiquinone) 23 KDA Subunit
J	1	Nadh-ubiquinone Oxidoreductase Chain 6
K	1	Nadh-ubiquinone Oxidoreductase Chain 4L
L	1	Nadh-ubiquinone Oxidoreductase Chain 5
M	1	Nadh-ubiquinone Oxidoreductase Chain 4
N	1	Nadh-ubiquinone Oxidoreductase Chain 2
O	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 10, Mitochondrial
P	1	Nadh Dehydrogenase (Ubiquinone) 39 KDA Subunit, Isoform a
Q	1	Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 4, Mitochondrial
R	1	Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 6, Mitochondrial
T U	2	Acyl Carrier Protein, Mitochondrial
V	1	Nadh Dehydrogenase (Ubiquinone) 13 KDA B Subunit
W	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 6
X	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 8
Y	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 11
Z	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 13
a	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 1
b	1	Rh45008p
d	1	Nadh Dehydrogenase [ubiquinone] 1 Subunit C2
e	1	Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 5
f	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 1
g	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 11, Mitochondrial
h	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 5, Mitochondrial
i	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 6
j	1	Geo11417p1
k	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 3
l	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 8, Mitochondrial
m	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 4
n	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 9
o	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 7
p	1	Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 10
q	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 12
r	1	Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 7
s	1	Nadh Dehydrogenase [ubiquinone] Flavoprotein 3, Mitochondrial
Chemicals and Non-standard biopolymers (39 molecules)
1	3	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2	16	1,2-Distearoyl-sn-glycerophosphoethanolamine
3	6	IRON/SULFUR CLUSTER
4	4	CARDIOLIPIN
5	2	FE2/S2 (INORGANIC) CLUSTER
6	1	FLAVIN MONONUCLEOTIDE
7	1	SODIUM ION
8	1	Ubiquinone-9
9	1	2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
10	1	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
11	1	ZINC ION
12	2	~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303