7MF0: Co-crystal structure of PERK with inhibitor (R)-2-amino-N-cyclopropyl-5-(4-(2-(3,5-difluorophenyl)-2-hydroxyacetamido)-2-methylphenyl)nicotinamide

PDB ID: 7MF0Download
MMDB ID: 202194
PDB Deposition Date: 2021/4/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.809  Å
Source Organism:
Similar Structures:
Biological Unit for 7MF0: monomeric; determined by author
Molecular Components in 7MF0
Label Count Molecule
Protein (1 molecule)
1
Eukaryotic Translation Initiation Factor 2-alpha Kinase 3,eukaryotic Translation Initiation Factor 2-alpha Kinase 3
(Gene symbol: EIF2AK3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-amino-N-cyclopropyl-5-(4-{[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino}-2-methylphenyl)pyridine-3-carboxamide2-amino-N-cyclopropyl-5-(4-{[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino}-2-methylphenyl)pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303