7DXG: Structure of SAR7334-bound TRPC6 at 2.9 angstrom

PDB ID: 7DXGDownload
MMDB ID: 211275
PDB Deposition Date: 2021/1/18
Updated in MMDB: 2022/08
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7DXG: tetrameric; determined by author
Molecular Components in 7DXG
Label Count Molecule
Proteins (4 molecules)
4
Short Transient Receptor Potential Channel 6
(Gene symbol: TRPC6)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
4
ZINC IONZINC ION
2
8
CALCIUM IONCALCIUM ION
3
16
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
4
4
4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile
5
4
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
6
4
[(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate[(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303