5H17: EED in complex with PRC2 allosteric inhibitor EED210

PDB ID: 5H17Download
MMDB ID: 146720
PDB Deposition Date: 2016/10/8
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5H17: dimeric; determined by author and by software (PISA)
Molecular Components in 5H17
Label Count Molecule
Proteins (2 molecules)
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
1
Histone-lysine N-methyltransferase Ezh2
(Gene symbol: EZH2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3R,4aS,10aS)-6-methoxy-3-[(3-methoxyphenyl)methyl]-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline(3R,4aS,10aS)-6-methoxy-3-[(3-methoxyphenyl)methyl]-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303