6QZH: Structure of the human CC Chemokine Receptor 7 in complex with the intracellular allosteric antagonist Cmp2105 and the insertion protein Sialidase NanA

PDB ID: 6QZHDownload
MMDB ID: 179193
PDB Deposition Date: 2019/3/11
Updated in MMDB: 2019/09
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6QZH: monomeric; determined by author and by software (PISA)
Molecular Components in 6QZH
Label Count Molecule
Protein (1 molecule)
1
C-C Chemokine Receptor Type 7,sialidase A,c-c Chemokine Receptor Type 7
(Gene symbol: CCR7)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
2
1
3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide
3
1
SODIUM IONSODIUM ION
4
2
D(-)-TARTARIC ACIDD(-)-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303