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    PRPF4 pre-mRNA splicing tri-snRNP complex factor PRPF4 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 464671, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRPF4provided by VGNC
    Official Full Name
    pre-mRNA splicing tri-snRNP complex factor PRPF4provided by VGNC
    Primary source
    VGNC:VGNC:4830
    Locus tag
    CK820_G0012524
    See related
    Ensembl:ENSPTRG00000021274
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See PRPF4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (25153192..25170346, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (93698427..93715516)

    Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene WD repeat domain 31 Neighboring gene ring finger protein 183 Neighboring gene cell division cycle 26 Neighboring gene uncharacterized LOC134807723 Neighboring gene solute carrier family 31 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables U4 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U6 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    U4/U6 small nuclear ribonucleoprotein Prp4
    Names
    PRP4 pre-mRNA processing factor 4 homolog
    pre-mRNA processing factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      25153192..25170346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009457111.5 → XP_009455386.1  U4/U6 small nuclear ribonucleoprotein Prp4 isoform X1

      See identical proteins and their annotated locations for XP_009455386.1

      UniProtKB/TrEMBL
      A0A2I3RCN1, A0A2J8NCY1, A0A6D2X506, H2QXQ4
      Related
      ENSPTRP00000036338.3
      Conserved Domains (3) summary
      smart00500
      Location:103 → 141
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      cd00200
      Location:233 → 519
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:234 → 271
      7WD40; WD40 repeat [structural motif]

    2. XM_520198.8 → XP_520198.3  U4/U6 small nuclear ribonucleoprotein Prp4 isoform X2

      See identical proteins and their annotated locations for XP_520198.3

      UniProtKB/TrEMBL
      A0A2I3RCN1, A0A2J8NCY8, A0A8I3B1G0, K7ADM8, K7CAW1
      Related
      ENSPTRP00000062395.1
      Conserved Domains (3) summary
      smart00500
      Location:102 → 140
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      cd00200
      Location:232 → 518
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:233 → 270
      7WD40; WD40 repeat [structural motif]

    3. XM_016961461.4 → XP_016816950.1  U4/U6 small nuclear ribonucleoprotein Prp4 isoform X3

      Conserved Domains (2) summary
      cd00200
      Location:8 → 276
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:42 → 78
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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