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    LAMA2 laminin subunit alpha 2 [ Bufo bufo (common toad) ]

    Gene ID: 120998483, updated on 21-Mar-2024

    Summary

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    Gene symbol
    LAMA2
    Gene description
    laminin subunit alpha 2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bufo bufo
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo
    Orthologs
    human mouse all
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    Genomic context

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    See LAMA2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    65
    Annotation release Status Assembly Chr Location
    100 current aBufBuf1.1 (GCF_905171765.1) 4 NC_053392.1 (368254191..369339421)

    Chromosome 4 - NC_053392.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene small nucleolar RNA SNORD71 Neighboring gene uncharacterized LOC120998484 Neighboring gene enoyl-[acyl-carrier-protein] reductase, mitochondrial-like Neighboring gene lamina-associated polypeptide 2 Neighboring gene Rho GTPase activating protein 18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_053392.1 Chromosome 4 Reference aBufBuf1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in basement membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit alpha-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Bufo bufo Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference aBufBuf1.1

    Genomic

    1. NC_053392.1 Reference aBufBuf1.1

      Range
      368254191..369339421
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040429125.1 → XP_040285059.1  laminin subunit alpha-2 isoform X1

      Conserved Domains (11) summary
      smart00136
      Location:30 → 280
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:963 → 1007
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1225 → 1355
      LamB; Laminin B domain
      smart00282
      Location:2156 → 2297
      LamG; Laminin G domain
      cd00055
      Location:913 → 960
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2941 → 3093
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1766 → 2126
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam06008
      Location:1584 → 1843
      Laminin_I; Laminin Domain I
      pfam06009
      Location:2028 → 2160
      Laminin_II; Laminin Domain II
      cl02548
      Location:579 → 706
      Laminin_B; Laminin B (Domain IV)
      cl22855
      Location:1357 → 1460
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    2. XM_040429126.1 → XP_040285060.1  laminin subunit alpha-2 isoform X2

      Conserved Domains (12) summary
      smart00136
      Location:30 → 280
      LamNT; Laminin N-terminal domain (domain VI)
      smart00180
      Location:963 → 1007
      EGF_Lam; Laminin-type epidermal growth factor-like domai
      smart00281
      Location:1225 → 1355
      LamB; Laminin B domain
      smart00282
      Location:2156 → 2297
      LamG; Laminin G domain
      cd00055
      Location:913 → 960
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:2935 → 3087
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      TIGR02168
      Location:1766 → 2126
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd00185
      Location:1385 → 1439
      TNFRSF; CRD3 [structural motif]
      pfam06008
      Location:1584 → 1843
      Laminin_I; Laminin Domain I
      pfam06009
      Location:2028 → 2160
      Laminin_II; Laminin Domain II
      cl02548
      Location:579 → 706
      Laminin_B; Laminin B (Domain IV)
      cl22855
      Location:1357 → 1460
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    Nucleotide Protein
    Heading Accession and Version

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