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    Ago2 argonaute RISC catalytic component 2 [ Fukomys damarensis (Damara mole-rat) ]

    Gene ID: 104872895, updated on 12-Mar-2024

    Summary

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    Gene symbol
    Ago2
    Gene description
    argonaute RISC catalytic component 2
    Locus tag
    H920_11777
    See related
    Ensembl:ENSFDAG00000004759
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Fukomys damarensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
    Orthologs
    human mouse all
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    Genomic context

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    See Ago2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900917.1 (81888597..81963343, complement)
    101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011045702.1 (294984..371327, complement)

    NW_022900917.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104872847 Neighboring gene chromatin accessibility complex subunit 1 Neighboring gene uncharacterized LOC104872851 Neighboring gene protein tyrosine kinase 2 Neighboring gene U1 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables endoribonuclease activity, cleaving siRNA-paired mRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RISC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein argonaute-2
    Names
    Protein argonaute-2
    argonaute 2, RISC catalytic component

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference DMR_v1.0_HiC Primary Assembly

    Genomic

    1. NW_022900917.1 Reference DMR_v1.0_HiC Primary Assembly

      Range
      81888597..81963343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_019209782.2 → XP_019065327.1  protein argonaute-2

      UniProtKB/TrEMBL
      A0A091D6V7
      Conserved Domains (4) summary
      cd02846
      Location:181 → 301
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:346 → 771
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:130 → 180
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:46 → 120
      ArgoN; N-terminal domain of argonaute

    2. XM_019209783.2 → XP_019065328.1  protein argonaute-2

      UniProtKB/TrEMBL
      A0A091D6V7
      Related
      ENSFDAP00000016334.1
      Conserved Domains (4) summary
      cd02846
      Location:181 → 301
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:346 → 771
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:130 → 180
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:46 → 120
      ArgoN; N-terminal domain of argonaute

    3. XM_019209784.2 → XP_019065329.1  protein argonaute-2

      UniProtKB/TrEMBL
      A0A091D6V7
      Conserved Domains (4) summary
      cd02846
      Location:181 → 301
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:346 → 771
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:130 → 180
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:46 → 120
      ArgoN; N-terminal domain of argonaute

    4. XM_019209781.2 → XP_019065326.1  protein argonaute-2

      UniProtKB/TrEMBL
      A0A091D6V7
      Related
      ENSFDAP00000016292.1
      Conserved Domains (4) summary
      cd02846
      Location:181 → 301
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:346 → 771
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:130 → 180
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:46 → 120
      ArgoN; N-terminal domain of argonaute
    Nucleotide Protein
    Heading Accession and Version

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