Analysis of mammary tumors from mutants lacking stem cell antigen-1 (Sca-1), a glycerophosphatidylinositol-anchored protein. Tumorigenesis induced by medroxyprogesterone and 7,12dimethylbenz(a)anthracene treatment. Results provide insight into the role of Sca-1 in mammary gland tumorigenesis.
Yuan H, Upadhyay G, Yin Y, Kopelovich L et al. Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptorĪ³ activation. Cancer Prev Res (Phila) 2012 Jan;5(1):51-60. PMID:Ā 21955520