Analysis of regulatory T (Treg) cells from mutants deficient for the transcription factor GATA-3. GATA-3 forms a complex with the transcription factor Fox3p, essential in the function of Treg cells. Results provide insight into the role of GATA-3 in the regulation of the Treg transcriptome.
Rudra D, deRoos P, Chaudhry A, Niec RE et al. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat Immunol 2012 Oct;13(10):1010-9. PMID: 22922362