Transcription factor Pax5 overexpression in Hodgkin lymphoma cell line L428
Summary:
Analysis of classical Hodgkin lymphoma (cHL) cell line L428 stably-transfected with a mifepristone-inducible PAX5-expression system. The L428-PAX5 cells were epigenetically modified by 5-aza-2'-deoxycytidine/TSA treatment. Results provide insight into the role of PAX5 in cHL.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Dimitrova L, Seitz V, Hecht J, Lenze D et al. PAX5 overexpression is not enough to reestablish the mature B-cell phenotype in classical Hodgkin lymphoma. Leukemia 2014 Jan;28(1):213-6. PMID: 23842424