Toxicogenomic response to gold nanoparticle exposure
Summary:
Analysis of age-synchronized L3 nematodes exposed to LC10 of gold nanoparticles (Au-NPs). The Au-NPs are used as a model for studying particle-specific effects of manufactured nanomaterials (MNMs). Results provide insight into in vivo particle-specific toxicity of Au-NPs to C. elegans.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Tsyusko OV, Unrine JM, Spurgeon D, Blalock E et al. Toxicogenomic responses of the model organism Caenorhabditis elegans to gold nanoparticles. Environ Sci Technol 2012 Apr 3;46(7):4115-24. PMID: 22372763