Analysis of kgb-1 mutants incubated with 1mM copper sulfate for 1hr. The conserved KGB-1 JNK mitogen-activated protein kinase pathway regulates the response to heavy metal stress. Results provide insight into molecular mechanisms underlying the heavy metal stress response.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Hattori A, Mizuno T, Akamatsu M, Hisamoto N et al. The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex. PLoS Genet 2013;9(2):e1003315. PMID: 23437011