Gli transcriptional repressor Gli3T effect on epithelioid carcinoma cell line Panc-1
Summary:
Analysis of epithelioid carcinoma Panc1 cells expressing Gli3T, a transcriptional repressor of Gli. Gli transcription factors are essential for Kras initiation of pancreatic tumorigenesis. Results provide insight into molecular mechanisms underlying pancreatic epithelial transformation.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA et al. The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. Proc Natl Acad Sci U S A 2012 Apr 24;109(17):E1038-47. PMID: 22493246
