Analysis of DAP12-deficient acute monocytic leukemia THP-1 cells that serve as a model of NHD, following treatment with 12-myristate 13-acetate (PMA). PMA is a known inducer of morphological differentiation of THP-1 cells. Results provide insight into molecular mechanisms underlying NHD pathology.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Satoh J, Shimamura Y, Tabunoki H. Gene expression profile of THP-1 monocytes following knockdown of DAP12, a causative gene for Nasu-Hakola disease. Cell Mol Neurobiol 2012 Apr;32(3):337-43. PMID: 22080356
