Retina response to hypoxia and subsequent reoxygenation: time course
Summary:
Analysis of retinas subjected to hypoxia for 6 hours and subsequent reoxygenation for up to 16 hours. Hypoxic preconditioning protects photoreceptors from light damage in animal model. Results provide insight into the molecular basis of this protective effect.
Thiersch M, Raffelsberger W, Frigg R, Samardzija M et al. Analysis of the retinal gene expression profile after hypoxic preconditioning identifies candidate genes for neuroprotection. BMC Genomics 2008 Feb 8;9:73. PMID: 18261226