Insulin-like growth factor-I effect on breast cancer cell line: time course
Summary:
Analysis of breast cancer MCF-7 cells stimulated with insulin-like growth factor-I (IGF-I) for 3 or 24 hours. High serum IGF-I levels are associated with an elevated risk of breast cancer. Results provide insight into the role of IGF-1 in the development and progression of breast cancer.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Creighton CJ, Casa A, Lazard Z, Huang S et al. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J Clin Oncol 2008 Sep 1;26(25):4078-85. PMID: 18757322
