Analysis of buccal epithelia from cigarette smokers. Cigarette smoke creates a field of injury in epithelial cells lining the respiratory tract. Results extend the concept of a smoking-induced field of injury beyond intrathoracic (bronchial) epithelia to extrathoracic epithelia that line the mouth.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Sridhar S, Schembri F, Zeskind J, Shah V et al. Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. BMC Genomics 2008 May 30;9:259. PMID: 18513428