Analysis of aneurysmal tissue from ascending aortas of patients with normal tricuspid aortic valves or abnormal bicuspid aortic valves (BAVs). BAV is a congenital anomaly associated with an increased risk for ascending aortic aneurysm (AscAAs). Results provide insight into the pathogenesis of AscAA.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Majumdar R, Miller DV, Ballman KV, Unnikrishnan G et al. Elevated expressions of osteopontin and tenascin C in ascending aortic aneurysms are associated with trileaflet aortic valves as compared with bicuspid aortic valves. Cardiovasc Pathol 2007 May-Jun;16(3):144-50. PMID: 17502243