Estren effect on the estrogen receptor alpha null uterus: time course
Summary:
Analysis of uteri from adult ovariectomized estrogen receptor alpha (ERalpha) null mutants treated with estren, estradiol, or 19-nortestosterone for 2 or 24 hours. Estren is a synthetic steroid. Results provide insight into the dependence of gene responses induced by estren in the uterus on ERalpha.
GPL891:
Agilent-011978 Mouse Microarray G4121A (Feature Number version)
Citation:
Hewitt SC, Collins J, Grissom S, Hamilton K et al. Estren behaves as a weak estrogen rather than a nongenomic selective activator in the mouse uterus. Endocrinology 2006 May;147(5):2203-14. PMID: 16469803