Beta-catenin activation effect on skin: time course
Summary:
Analysis of skin of deltaNB-cateninER transgenics following the activation of beta-catenin for up to 7 days. Onset and duration of beta-catenin activation in deltaNB-cateninER transgenics controlled by 4-hydroxytamoxifen. Results provide insight into how beta-catenin induces hair follicle growth.
Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T et al. Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell 2005 Jul;9(1):121-31. PMID: 15992546
