Breast cancer cells reexpressing estrogen receptor alpha response to 17beta-estradiol
Summary:
Analysis of the response of estrogen receptor (ER) negative MDA-MB-231 breast cancer cells infected with full-length ER alpha adenoviral constructs to treatment with 17beta-estradiol (E2). Results provide insight into the anti-proliferative effect of E2 on breast cancer cells reexpressing ER.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Moggs JG, Murphy TC, Lim FL, Moore DJ et al. Anti-proliferative effect of estrogen in breast cancer cells that re-express ERalpha is mediated by aberrant regulation of cell cycle genes. J Mol Endocrinol 2005 Apr;34(2):535-51. PMID: 15821115