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Series GSE2251 Query DataSets for GSE2251
Status Public on Feb 09, 2005
Title Anti-prolif. effect of E2 in breast cancer cells that re-exp. ERalpha is mediated by aberr. regulat. of cell cycle genes
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression changes caused by estrogen treatment of breast cancer cells that re-express ERalpha was investigated by infecting ER-negative MDA-MB-231 breast cancer cells for 24 h with recombinant adenovirus encoding full-length human ERalpha (Ad-ERalpha) or control vector (Ad-LacZ), and treating them with 0ยท01% ethanol (vehicle control) or 10-8 M 17beta-estradiol (E2). After 48 h of treatment, total RNA was isolated and used for transcript profiling on Affymetrix GeneChips. Three independent biological replicates of this experiment were carried out.
Keywords: ordered
Contributor(s) Moggs Jg, Murphy Tc, Lim F, Moore Dj, Stuckey R, Antrobus K, Kimber I, Orphanides G
Citation(s) 15821115
Submission date Feb 07, 2005
Last update date Aug 10, 2018
Contact name Fei Ling Lim
Phone +44 (0)1234222450
Organization name Unilever
Street address Colworth Science Park
City Sharnbrook
State/province Bedfordshire
ZIP/Postal code MK44 1LQ
Country United Kingdom
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (12)
GSM41346 AdERalpha+E2-8 JM3
GSM41347 AdERalpha+E2-8 JMTM5
GSM41348 AdERalpha+E2-8 JMTM19
BioProject PRJNA91353

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