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1. Input mutations:

Choose a file with mutations (in VCF, MAF, or trinucleotide format) and specify genome assembly below

OR paste mutations directly in the textbox:

2. Genome assembly release:

Classification method or similarity function:

Or try examples: a large sample in VCF format or a sample in MAF format. Note that genome assembly for the examples is set automatically.

Please cite MutaGene as Goncearenco A, Rager SL, Li M, Sang Q, Rogozin IB, Panchenko AR Exploring background mutational processes to decipher cancer genetic heterogeneity. Nucleic Acids Res. 2017; 45(W1):W514–W522.
Driver prediction method is described in Brown AL, Li M, Goncearenco A, Panchenko AR Finding driver mutations in cancer: Elucidating the role of background mutational processes. PLOS Computational Biology 2019; 15(4): e1006981.