Protein Family Models for Protein (Select 914217994) - Protein Family Models

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Links from Protein

Items: 8

Select item 4240421.

iron-containing alcohol dehydrogenase

Date:: 2024-08-14

Family Accession:: NF025065.5
Method:: HMM

Select item 4110542.

iron-containing alcohol dehydrogenase

GO Terms:

Molecular Function:: oxidoreductase activity (GO:0016491)

Molecular Function:: metal ion binding (GO:0046872)

Date:: 2024-08-14

Family Accession:: NF012678.5
Method:: HMM

Select item 4000343.

new record, indexing in progress

Family Accession:

Select item 3886934.

new record, indexing in progress

Family Accession:

Select item 3585955.

new record, indexing in progress

Family Accession:

Select item 3471236.

new record, indexing in progress

Family Accession:

Select item 2216757.

iron-containing alcohol dehydrogenase

iron-containing alcohol dehydrogenase catalyzes the iron-dependent reversible oxidation of alcohol to acetaldehyde with the simultaneous reduction of NAD(P) to NAD(P)H; similar to lactaldehyde reductase which catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol

Date:: 2018-06-26

Family Accession:: 10798391
Method:: Sparcle

Select item 507398.

lactaldehyde reductase

This clade of genes encoding iron-containing alcohol dehydrogenase (PF00465) proteins is generally found in apparent operons for the catabolism of rhamnose or fucose. Catabolism of both of these monosaccharides results in lactaldehyde which is reduced by this enzyme to 1,2 propanediol [1]. This protein is alternatively known by the name 1,2 propanediol oxidoreductase. This enzyme is active under anaerobic conditions in E. coli while being inactivated by reactive oxygen species under aerobic conditions [2]. Under aerobic conditions the lactaldehyde product of rhamnose and fucose catabolism is believed to be oxidized to lactate by a separate enzyme, lactaldehyde dehydrogenase.