Protein Family Models

The YjgF/YER057c/UK114 family, including a member protein that has been called endoribonuclease L-PSP (perchloric acid-soluble protein), is now called the RidA family, or more generally the Rid family, with subfamilies RidA and Rid1 through Rid7. YjgF from Salmonella enterica deaminates the toxic metabolite 2-amino acrylate and so was renamed RidA (reactive intermediate imine deaminase A). This HMM hits proteins that are members of multiple Rid subfamilies.

Date:

2024-08-14

RidA (reactive intermediate/imine deaminase A) family protein similar to Pseudomonas sp. 2-aminomuconate deaminase that hydrolyzes 2-aminomuconate to 4-oxalocrotonate, and releases ammonia in the modified meta-cleavage pathway by forming various compounds including acetaldehyde, pyruvic acid, acetyl-CoA, and succinate, that may enter the Krebs cycle

Date:

2024-05-21