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SWIM zinc finger family protein
This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organised into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (Pfam:PF00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts [1]. [1]. 12151216. SWIM, a novel Zn-chelating domain present in bacteria, archaea. and eukaryotes.. Makarova KS, Aravind L, Koonin EV;. Trends Biochem Sci 2002;27:384-386. (from Pfam)
SWIM (SWI2/SNF2 and MuDR) zinc finger family protein similar to Homo sapiens zinc finger SWIM domain-containing protein 7 that is involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents
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