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NAD(P)H-binding protein
NmrA family NAD(P)-binding protein
NmrA is a negative transcriptional regulator involved in the post-translational modification of the transcription factor AreA. NmrA is part of a system controlling nitrogen metabolite repression in fungi [1]. This family only contains a few sequences as iteration results in significant matches to other Rossmann fold families. [1]. 11726498. The structure of the negative transcriptional regulator NmrA. reveals a structural superfamily which includes the short-chain. dehydrogenase/reductases.. Stammers DK, Ren J, Leslie K, Nichols CE, Lamb HK, Cocklin S,. Dodds A, Hawkins AR;. EMBO J 2001;20:6619-6626. (from Pfam)
NAD-dependent epimerase/dehydratase family protein
This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions. [1]. 9174344. Structural analysis of UDP-sugar binding to UDP-galactose. 4-epimerase from Escherichia coli.. Thoden JB, Hegeman AD, Wesenberg G, Chapeau MC, Frey PA, Holden. HM;. Biochemistry 1997;36:6294-6304. (from Pfam)
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