Protein Family Models

This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B. (from Pfam)

Date:

2024-08-14

Date:

2024-08-14

This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid [1]. [1]. 12571357. Crystal structure of the plasmid maintenance system. epsilon/zeta: functional mechanism of toxin zeta and. inactivation by epsilon 2 zeta 2 complex formation.. Meinhart A, Alonso JC, Strater N, Saenger W;. Proc Natl Acad Sci U S A 2003;100:1661-1666. (from Pfam)

Date:

2024-08-14

Date:

2024-08-14

This family includes relatives of the G-domain of the SRP54 family of proteins. [1]. 9002525. Crystal structure of the NG domain from the signal-recognition. particle receptor FtsY.. Montoya G, Svensson C, Luirink J, Sinning I;. Nature 1997;385:365-368. (from Pfam)

Date:

2024-08-14

signal recognition particle-docking protein FtsY is a GTPase involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane; acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)

Date:

2024-09-09

FtsY, a GTPase, serves as a membrane receptor for the signal recognition particle. It belongs to a system that lets proteins with an N-terminal signal peptide to resume translation and insert into the membrane. In E.coli, ftsY is located near the similarly named genes ftsE and ftsX, but their products are involved instead in cell division.

Gene:

ftsY

Date:

2024-06-04