Protein Family Models

This domain is about 100 amino acid residues in length. It is found in the MazG protein from E. coli. It contains four conserved negatively charged residues that probably form an active site or metal binding site. This domain is found in isolation in some proteins as well as associated with Pfam:PF00590. This domain is clearly related to Pfam:PF01503 another pyrophosphohydrolase involved in histidine biosynthesis. This family may be structurally related to the NUDIX domain Pfam:PF00293 (Bateman A pers. obs.). [1]. 12218018. MazG, a nucleoside triphosphate pyrophosphohydrolase, interacts. with Era, an essential GTPase in Escherichia coli.. Zhang J, Inouye M;. J Bacteriol 2002;184:5323-5329. (from Pfam)

Date:

2024-08-14

Gene:

mazG

Date:

2021-02-12

nucleoside triphosphate pyrophosphohydrolase hydrolyzes NTPs into their corresponding nucleoside monophosphates and pyrophosphate

Date:

2023-03-01

YabN family protein contains an N-terminal S-AdoMet-dependent tetrapyrrole methylase domain and a MazG family nucleoside triphosphate pyrophosphohydrolase domain, similar to Bacillus subtilis protein YabN

Date:

2020-10-23

This family of prokaryotic proteins has no known function. It includes the uncharacterized protein MazG in E. coli.

Date:

2019-09-10