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Links from Protein

Items: 12

1.

DapH/DapD/GlmU-related protein

Members of this family share a hexapeptide repeat-containing domain with acetyltransferases and succinyltransferases such as DapH, DapD, and GlmU.

Date:
2024-08-14
Family Accession:
NF025953.5
Method:
HMM
2.

LpxD N-terminal domain-containing protein

UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) catalyses an early step in lipid A biosynthesis: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] -> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein] [1]. Members of this family also contain a hexapeptide repeat (Pfam:PF00132). This family constitutes the non-repeating region of LPXD proteins. [1]. 8366125. The firA gene of Escherichia coli encodes. UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase.. The third step of endotoxin biosynthesis.. Kelly TM, Stachula SA, Raetz CR, Anderson MS;. J Biol Chem 1993;268:19866-19874. (from Pfam)

GO Terms:
Biological Process:
lipid A biosynthetic process (GO:0009245)
Molecular Function:
acyltransferase activity, transferring groups other than amino-acyl groups (GO:0016747)
Date:
2024-08-14
Family Accession:
NF016494.5
Method:
HMM
3.

transferase-like hexapeptide repeat-containing protein

Date:
2024-08-14
Family Accession:
NF012360.5
Method:
HMM
4.
new record, indexing in progress
Family Accession:
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
Family Accession:
7.
new record, indexing in progress
Family Accession:
8.
new record, indexing in progress
Family Accession:
9.
new record, indexing in progress
Family Accession:
10.

UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

Adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis

GO Terms:
Biological Process:
lipid A biosynthetic process (GO:0009245)
Molecular Function:
N-acyltransferase activity (GO:0016410)
Date:
2021-10-20
Family Accession:
NF002060.0
Method:
HMM
11.

UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

This HMM describes LpxD, an enzyme for the biosynthesis of lipid A, a component oflipopolysaccharide (LPS) in the outer membrane outer leaflet of most Gram-negative bacteria. Some differences are found between lipid A of different species. This protein represents the third step from UDP-N-acetyl-D-glucosamine. The group added at this step generally is 14:0(3-OH) (myristate) but may vary; in Aquifex it appears to be 16:0(3-OH) (palmitate).

Gene:
lpxD
GO Terms:
Biological Process:
lipid A biosynthetic process (GO:0009245)
Molecular Function:
N-acyltransferase activity (GO:0016410)
Date:
2021-04-27
Family Accession:
TIGR01853.1
Method:
HMM
12.

LpxD family protein

LpxD family protein

Date:
2017-03-02
Family Accession:
11437199
Method:
Sparcle
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